PW01-005 – Effects of placebo and colchicine on FMF patients
نویسندگان
چکیده
منابع مشابه
PW01-005 – Effects of placebo and colchicine on FMF patients
Results A total amount of 50 patients (22 girls, 28 boys) were included. The median age of the patients was 8.5 years (2.5-17.5). 78% of the patients suffered from fever attacks suggestive of FMF every 1-4 weeks. The attack interval of the remaining patients was more than one month. At the time of admission, the median values for ESR and CRP were; 24.5 mm/hr (1-100) and 2 mg/dl (0-31), respecti...
متن کاملPW01-007 – Colchicine brand switching in FMF patients
Introduction In July of 2009 the U.S. Food and Drug Administration enacted new regulation of colchicine under the “Unapproved Drugs Program.” Like other old drugs that were on the market before the existence of the FDA, colchicine had never been subjected to FDA-required safety and efficacy trials. One company elected to put colchicine through the FDA’s approval protocol and when approval was g...
متن کاملPW01-025 – Definition of colchicine resistance in FMF
E Demirkaya, C Acikel, A Tufan, A Kucuk, A Berdeli, A Gul, AM Onat, A Delibas, A Duzova, A Dinc, O Yavascan, O Kasapcopur, B Makay, B Goker, B Sozeri, B Kisacik, E Comak, E Unsal, E Erken, E Gunal, E Baskin, F Yalcinkaya, F Yildiz, F Gok, G Basbozkurt, G Ozcelik, G Demircin, H Poyrazoglu, H Erdem, H Direskeneli, H Ozer, H Ozdogan, I Simsek, I Dursun, I Gokce, M Tunca, M Gurgoze, N Cakar, N Akin...
متن کاملPW01-002 – Colchicine resistant FMF in Turkish children
Results Eleven patients with mean age of 12,7±7,7 years (median 14, ranging 1,5-23 years) were studied. These patients were on colchicine treatment for a mean of 5,5±4,2 years. In one patient initially etanercept was used however, this was switched to anakinra since there was no repsonse to anti TNF treatment. A total of 7 patiets were started anakinra, however, 2 had local reactions and 2 was ...
متن کاملOR7-005 – Canakinumab in childhood colchicine resistant FMF
Introduction Familial Mediterranean Fever (FMF) is the most common hereditary autoinflammatory syndrome affecting >10,000 people in Israel. FMF is caused by mutations in the MEFV gene, which encodes for the pyrin protein that is part of the inflammation complex that activates IL-1b. Evidence from case reports/series and one controlled study supports IL-1 blockage as a potential treatment for FM...
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ژورنال
عنوان ژورنال: Pediatric Rheumatology
سال: 2013
ISSN: 1546-0096
DOI: 10.1186/1546-0096-11-s1-a58